+ 44 28 9097 6474 V.Tiwari@qub.ac.uk

We are particularly interested in studying how cell-fates are specified during developmentand miss-specified in diseases.

The research in my lab is aimed at achieving an integrated molecular and systems-level understanding of the mechanisms by which epigenetic machinery and transcription factors contribute to transcriptional reprogramming that defines cell-type identity during development and how this communication is altered in diseases such as cancer. To investigate these questions, we employ a multidisciplinary approach combining cutting-edge epigenetics and genomics together with computational biology tools in sophisticated and defined models of cellular differentiation and carcinogenesis.

Research Interests Epigenetic Regulation of Differentiation and Disease

Researches The Key Topics of Research

  • Transcription Factors and Cell-Fate Specification
  • Epigenomics of Cell-type Identity
  • Signaling to Chromatin Crosstalk
  • Epigenetic Regulation of Neurogenesis
  • Chromatin and Cancer
  • Systems Biology of Gene Regulatory Networks